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Error message when trying to send out going email

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January 27, 2024 About 2 days ago I started to get the following error message while trying to send any/all emails.

Sending of the message failed. An error occurred while sending mail. The mail server responded: <ec2-15-181-96-135.compute-1.amazonaws.com[15.181.96.135]>: Client host rejected: Access denied.

Prior to this, everything has always worked well for years. I contacted my service provider and spend hours going over all settings and everything look OK. I can send emails out on my iPad with all of the same setting with no problem. I made no changes or updates to my PC. I am a retired software engineer and very knowledge able about software and can not determine the issue. Since nothing has changed with my PC, or with my service provider, that leaves a problem with Thunderbird? Any ideas?

January 27, 2024 About 2 days ago I started to get the following error message while trying to send any/all emails. Sending of the message failed. An error occurred while sending mail. The mail server responded: <ec2-15-181-96-135.compute-1.amazonaws.com[15.181.96.135]>: Client host rejected: Access denied. Prior to this, everything has always worked well for years. I contacted my service provider and spend hours going over all settings and everything look OK. I can send emails out on my iPad with all of the same setting with no problem. I made no changes or updates to my PC. I am a retired software engineer and very knowledge able about software and can not determine the issue. Since nothing has changed with my PC, or with my service provider, that leaves a problem with Thunderbird? Any ideas?

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While I just don't see where the host response comes into it. That amazon IP address is on at least on mail blacklist for spam. https://cleantalk.org/blacklists/15.181.96.135

What is not clear is if you have a domain you are sending from and it is a shard server and others on the server have caused a blacklist, or if you are using a VPN that has managed to get a bad rep for it's endpoint.