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I have Trend Micro Security, Mozilla FoxFire? is there a conflict here

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When I am trying to read or open my Emails, I am constantly getting this message "Thunderbird is not responding". Why is this and what can I or you do to stop this. It is very frustrating because it is happening most of the time, for years. Took our computer in and they removed any interfering programs. Still having the same not responding. Changed internet from Peak to Comcast still have the Not Responding. Have Trend Micro Security. If this does not get resolved in the next week will remove Mozilla and go to gmail.

When I am trying to read or open my Emails, I am constantly getting this message "Thunderbird is not responding". Why is this and what can I or you do to stop this. It is very frustrating because it is happening most of the time, for years. Took our computer in and they removed any interfering programs. Still having the same not responding. Changed internet from Peak to Comcast still have the Not Responding. Have Trend Micro Security. If this does not get resolved in the next week will remove Mozilla and go to gmail.

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First I would check if the Trend software is part of the issue by restarting Windows in "Safe mode with networking". If Thunderbird works better then it suggests Trend is the cause of the delays, and I would look into how to exclude Thunderbird from its scanning.

If Windows' safe mode doesn't help, I'd try Thunderbird in its own safe mode just to rule about any extensions, add-ons or other customizations,.

Generally we advise against allowing real-time scanning by anti-virus software to act on email. Thunderbird stores all the messages you see in a folder in one big file, and if an anti-virus product thinks a message is dangerous, it is likely to quarantine the file that contains the offending message, and that means the whole folder goes with it.

The "on-demand" part of your security software should be allowed to continue to operate, so it will step forward if you try to run anything that arrived as an attachment.