I can receive E-Mails using thunderbird as a client but no send them. If I use the Microsoft web portal I can send and receive E-Mail messages. When I send an email using any Microsoft E-Mail account I just receive the following message in a window. The Window is labeled as "Send Message Error". The message that I receive is; Sending of the message failed. The message could not be sent because the connection to Outgoing server (SMTP) smtp.office365.com timed out. Try again. I have tried the following: Changing client account settings, update software, searched the knowledge base, deleted the accounts and recreated them, removed all thundebird software and reinstalling. What has caused this and how can I get the client the work again.