Perform the suggestions mentioned in the following articles:

• Check for new versions of your add-ons
• Troubleshoot extensions, themes and hardware acceleration issues to solve common Firefox problems

Check and tell if its working.

Firefox 10 has many problems and I found the solution did an update to firefox 11 beta and so far everything is working well.

FF10 is the BIGGEST upgrade mess ever! Scared to try a beta! LOL

Sorry, but still having these issues. Tried several things listed with no luck. Like I said, it all started when I upgraded to FF10 from FF9.01. Some extension just will not stayed enabled and lso Personas will not stay enabled after I relaunch. As lomg as I don't restarted, they stay enabled. Very irritating!

Anyone else having this issue?

Create a New Profile as a test to check if your current profile is causing the problems.

• Basic Troubleshooting - Make a New Profile

IF that New Profile works then you can recover your History, Bookmarks and Passwords from the Old Profile.

• Recover important data from an old profile

Check and tell if its working.

See also:

• http://kb.mozillazine.org/Preferences_not_saved
• https://support.mozilla.org/kb/Preferences+are+not+saved